14S(15R)-EET methyl ester, CAS [[110901-52-5]]

Produktübersicht

• Artikelname: 14S(15R)-EET methyl ester, CAS [[110901-52-5]]
• Artikelnummer: TGM-T85051
• Hersteller Artikelnummer: T85051
• Alternativnummer: TGM-T85051-10UG,TGM-T85051-25UG,TGM-T85051-50UG,TGM-T85051-100UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

14S(15R)-EET methyl ester, an oxylipin derived from arachidonic acid through cytochrome P450 metabolism, demonstrates specific biological activities. It exhibits affinity for isolated guinea pig monocytes, evidenced by a competitive binding assay with a Ki value of 612.5 nM using [3H]14(15)-EET. This compound notably enhances the dilation of precontracted isolated canine epicardial arterioles (EC50= 4 pM) and denuded porcine subepicardial arterioles (EC50= 3 pM), indicating potent vasodilatory effects. Unlike its isomer 14R(15S)-EET, 14S(15R)-EET methyl ester does not inhibit COX activity in enzyme assays or affect isolated platelets, highlighting its distinct functional profile.

Produkteigenschaften

• Molekulargewicht: 334.49
• CAS Nummer: [110901-52-5]
• Formel: C21H34O3
• Target-Kategorie: Others|||Drug Metabolite