BTL-MK (Compound 19) is an orally active antiallergic agent that inhibits degranulation of mast cells with an IC50 of 6.7 µM by binding to the inhibitory receptor FcgammaRIIB. BTL-MK improves metabolic stability in human liver microsomes and ameliorates the allergic response in an Ovalbumin-induced food allergy mice model. It exhibits good pharmacokinetic characteristics with metabolic stability [1].
Molekulargewicht:
408.44
CAS Nummer:
[2758569-43-4]
Formel:
C24H24O6
Target-Kategorie:
Others
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