CRT0066101 is a potent and orally active protein kinase D inhibitor with low-nanomolar activity against PKD1, PKD2, and PKD3, while also inhibiting PIM2, CRT0066101 demonstrates significant anti-inflammatory efficacy in lipopolysaccharide-induced lung injury models as well as anticancer activity, supporting its use in inflammation and oncology research.
Molekulargewicht:
338.41
CAS Nummer:
[956123-34-5]
Formel:
C18H22N6O
Target-Kategorie:
Pim|||Serine/threonin kinase
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