E722-2648 is a potent inhibitor of the beta-catenin/BCL9 complex, specifically preventing its formation and inhibiting Wnt activity. It disrupts cholesterol homeostasis through increased cholesterol esterification and accumulation of lipid droplets. Additionally, E722-2648 exhibits antitumor activity [1].
Molekulargewicht:
390.61
CAS Nummer:
[931963-55-2]
Formel:
C21H30N2OS2
Target-Kategorie:
Wnt/beta-catenin
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