HSD17B13-IN-36 (compound 116) serves as a potent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), exhibiting an IC50 of <0.1 µM with estradiol as substrates. This compound is significant in the management of nonalcoholic fatty liver diseases (NAFLDs), including NASH (nonalcoholic steatohepatitis) [1].
Molekulargewicht:
433.43
CAS Nummer:
[2730027-86-6]
Formel:
C20H17F2N3O4S
Target-Kategorie:
Dehydrogenase
T86625
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