HSD17B13-IN-71 (Compound 149), an effective inhibitor of hydroxysteroid 17beta-dehydrogenase 13 (HSD17B13), displays potent activity with an IC 50 value of 0.1 µM against estradiol. This compound is applicable in the study of various disorders including liver diseases, metabolic diseases, and cardiovascular conditions such as NAFLD or NASH, in addition to drug-induced liver injury (DILI) [1].
Molekulargewicht:
588.31
CAS Nummer:
[2770247-40-8]
Formel:
C25H16Cl2F5N3O4
Target-Kategorie:
Dehydrogenase
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