HSD17B13-IN-75 (Compound 21) serves as an inhibitor targeting hydroxysteroid 17beta-dehydrogenase 13 (HSD17B13), demonstrating an IC 50 value of 0.1 µM for estradiol. Its applications are primarily in the research fields addressing liver diseases, metabolic disorders, and cardiovascular conditions, including NAFLD, NASH, and drug-induced liver injury (DILI) [1].
Molekulargewicht:
484.31
CAS Nummer:
[2770246-20-1]
Formel:
C24H16Cl2FN3O3
Target-Kategorie:
Dehydrogenase
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