HSD17B13-IN-80 (Compound 151) serves as an inhibitor for hydroxysteroid 17beta-dehydrogenase 13 (HSD17B13), demonstrating potent activity with an IC 50 0.1 µM against estradiol. It is primarily utilized in the investigation of liver, metabolic, and cardiovascular diseases including NAFLD, NASH, and drug-induced liver injury (DILI) [1].
Molekulargewicht:
536.33
CAS Nummer:
[2770247-42-0]
Formel:
C25H18Cl2F3N3O3
Target-Kategorie:
Dehydrogenase
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