InhA-IN-7 (Compound 11), a derivative of Triclocan, shows inhibitory activity against enoyl-acyl carrier protein reductase (InhA) with an IC50 of 96 nM. It effectively inhibits the proliferation of both wildtype and mutant strains of Mycobacterium tuberculosis, exhibiting minimum inhibitory concentrations (MICs) ranging from 19 to 75 µM [1].
Molekulargewicht:
325.23
CAS Nummer:
[952588-17-9]
Formel:
C17H18Cl2O2
Target-Kategorie:
Antibacterial
T86721
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