KT-333 ammonium, CAS [[2839758-34-6]] Preis auf Anfrage
Artikelnummer:
TGM-T86788
Hersteller Artikelnummer:
T86788
Alternativnummer:
TGM-T86788-10MG,TGM-T86788-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
KT-333 ammonium (Compound A) acts as a molecular glue that targets and promotes the degradation of the STAT3 protein through the ubiquitin-proteasome system. This compound achieves selective degradation by binding simultaneously to the STAT3 protein and the E3 ubiquitin ligase von Hippel-Lindau protein (VHL). It exhibits strong selectivity and efficacy in degrading STAT3, possessing notable antitumor properties. KT-333 ammonium is particularly useful for research on hematologic malignancies, including large granular lymphocytic leukemia (LGL-L), peripheral T-cell lymphoma (PTCL), and cutaneous T-cell lymphoma (CTCL) [1].
Molekulargewicht:
1274.81
CAS Nummer:
[2839758-34-6]
Formel:
C60H77ClN11O14PS
Target-Kategorie:
Molecular Glues|||STAT
T86788
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