Mca-SEVNLDAEFK(Dnp), CAS [[1802078-31-4]] Preis auf Anfrage
Artikelnummer:
TGM-T86868
Hersteller Artikelnummer:
T86868
Alternativnummer:
TGM-T86868-10MG,TGM-T86868-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
Mca-SEVNLDAEFK(Dnp) is a peptide FRET substrate for Beta-secretase 1 (BACE-1), featuring the Swedish Lys-Met/Asn-Leu mutation at the beta-secretase cleavage site of the amyloid precursor protein (APP). Cleavage at the -Leu-Asp- site of Mca-SEVNLDAEFK(Dnp) releases the highly fluorescent 7-methoxycoumarin (Mca) fragment, which is freed from the quenching effect of the 2,4-dinitrophenyl (Dnp) internal quencher, leading to a significantly increased fluorescence intensity that is easily detectable.
Molekulargewicht:
1533.5
CAS Nummer:
[1802078-31-4]
Formel:
C68H88N14O27
Target-Kategorie:
Others|||Beta-Secretase
T86868
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