NEO214, CAS [[1361198-80-2]]

Produktübersicht

• Artikelname: NEO214, CAS [[1361198-80-2]]
• Artikelnummer: TGM-T86992
• Hersteller Artikelnummer: T86992
• Alternativnummer: TGM-T86992-1MLX10MM(INDMSO),TGM-T86992-1MG,TGM-T86992-5MG,TGM-T86992-10MG,TGM-T86992-25MG,TGM-T86992-50MG,TGM-T86992-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

NEO214 is an autophagy inhibitor obtained by covalently conjugating rolipram, a PDE4 inhibitor, with perillyl alcohol. It possesses anticancer activity and blood-brain barrier (BBB) permeability, blocks autophagosome-lysosome fusion, thereby inhibiting autophagic flux and inducing glioma cell death, which is associated with mTOR activation and aggregation of the transcription factor TFEB. NEO214 inhibits macroautophagy/autophagy in glioblastoma cells and has the potential to overcome chemoresistance in glioblastoma.

Produkteigenschaften

• Molekulargewicht: 453.57
• Reinheit: 95.63%
• CAS Nummer: [1361198-80-2]
• Formel: C27H35NO5
• Target-Kategorie: mTOR|||Autophagy

Bilder

T86992