PROTAC KRAS G12C degrader-2, CAS [[2378257-72-6]] Preis auf Anfrage

Produktübersicht

• Artikelname: PROTAC KRAS G12C degrader-2, CAS [[2378257-72-6]] Preis auf Anfrage
• Artikelnummer: TGM-T87266
• Hersteller Artikelnummer: T87266
• Alternativnummer: TGM-T87266-10MG,TGM-T87266-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

PROTAC KRAS G12C degrader-2 (compound 432) is a targeted modulator of K-Ras protein hydrolysis that functions as a bifunctional PROTAC molecule, incorporating a cereblon inhibitor of apoptosis proteins (IAP) ligand on one terminus and a KRAS-binding moiety on the opposite end, thereby enabling selective recruitment of mutant KRAS G12C to the ubiquitin-proteasome system for controlled degradation and mechanistic investigation of KRAS-driven oncogenic signaling pathways.

Produkteigenschaften

• Molekulargewicht: 958.47
• CAS Nummer: [2378257-72-6]
• Formel: C51H53ClFN9O7
• Target-Kategorie: Ligands for E3 Ligase|||IAP

Bilder

T87266