Compound 21, also known as PLK1/BRD4-IN-3, acts as a selective dual inhibitor targeting both bromodomain 4 (BRD4) and polo-like kinase 1 (PLK1). It effectively inhibits BRD4-BD1, PLK1, and BRDT-BD1, exhibiting IC50 values of 0.059, 0.127, and 0.245 µM, respectively.
Molekulargewicht:
561.72
CAS Nummer:
[2251709-91-6]
Formel:
C31H43N7O3
Target-Kategorie:
PLK|||Epigenetic Reader Domain
T87990
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