Jobosic acid is a saturated fatty acid and a selective inhibitor of SARS-CoV-2. It inhibits the Mpro and the interaction between spike-RBD/ACE-2 with IC50 values of 7.5 µg/mL and 3 µg/mL, respectively. Jobosic acid also exhibits viral entry inhibition against the omicron variant of SARS-CoV-2.
Molekulargewicht:
256.42
CAS Nummer:
[223611-93-6]
Formel:
C16H32O2
Target-Kategorie:
SARS-CoV
T88022
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