LolCDE-IN-4 (Compound 1) demonstrates antibacterial potency by inhibiting the LolCDE complex and disrupting the release of lipoproteins from the inner membrane, showing efficacy against gram-negative bacteria such as Escherichia coli (MIC of 0.25-32 µg/ml) and Haemophilus influenzae.
Molekulargewicht:
335.4
CAS Nummer:
[1859918-13-0]
Formel:
C20H21N3O2
Target-Kategorie:
Antibacterial
T88061
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