EGFRT790M/L858R-IN-8 (compound 9) is a potent inhibitor of EGFR, specifically targeting the EGFRT790M/L858R mutations with an IC50 of 56.8 µM. This compound does not show significant antiproliferative effects on cancer cell lines A549, A431, and NHI-H1975.
Molekulargewicht:
359.17
CAS Nummer:
[333419-97-9]
Formel:
C16H11BrN2O3
Target-Kategorie:
EGFR
T88087
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