SIC-19, a SIK2 inhibitor, functions by promoting the degradation of SIK2 protein via the ubiquitination pathway. It inhibits the growth of cancer cells and sensitizes cells, ovarian cancer organoids, and xenograft models to PARP inhibitors (such as Olaparib).
Molekulargewicht:
574.67
CAS Nummer:
[713112-69-7]
Formel:
C29H26N4O5S2
Target-Kategorie:
SIK
T88487
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