RWJ-58643 is a beta-trypsin and trypsin inhibitor used in studies to inhibit allergic inflammatory conditions. The compound was effective in reducing nasal allergy symptoms, eosinophil infiltration, and interleukin-5 (IL-5) levels at a lower dose (100 mg). However, at higher doses (300 mg and 600 mg), an increase in eosinophils and elevated IL-5 levels were observed, showing a clear dose-dependent response.
Molekulargewicht:
446.52
CAS Nummer:
[287183-00-0]
Formel:
C20H26N6O4S
Target-Kategorie:
Others|||Serine Protease
T88503
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