MT-1207 is a selective antagonist of adrenergic alpha1 and 5-HT2A receptors with oral activity. It exhibits IC50 values of <0.1 nM for alpha1A, 0.15 nM for alpha1B, 1.40 nM for alpha1D, and 0.27 nM for 5-HT2A. In the 2K2C rat model, MT-1207 effectively reduces blood pressure (BP) without impairing renal function. As a multitarget inhibitor, MT-1207 has potential for research in vasodilation.
Molekulargewicht:
428.98
CAS Nummer:
[1610794-70-1]
Formel:
C21H25ClN6S
Target-Kategorie:
5-HT Receptor|||Adrenergic Receptor
T88520
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