UNC10245380 is a CIB1 inhibitor with an IC50 of 8 µM. It also inhibits the phosphorylation of AKT and ERK while upregulating the expression of TRAIL-R1/D5. UNC10245380 specifically kills cancer cells that are dependent on CIB1, demonstrating its potential value in the development of CIB1 probes and cancer research.
Target-Kategorie:
Akt|||ERK|||TNF
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