(+)-Crinatusin A1 (Compound (+)- 4) is a chalcone-monoterpene hybrid isolated from Cleistocalyx operculatus. It acts as an inhibitor of protein tyrosine phosphatase 1B (PTP1B), with an IC50 of 0.9 µM, suggesting potential as an antidiabetic agent.
Target-Kategorie:
Phosphatase
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