EGFR/HER2-IN-16 (compound 12K) is an effective dual-target inhibitor of EGFR (IC50=6.15 nM) and HER-2 (IC50=9.78 nM), exhibiting antitumor activity. This compound inhibits migration of SK-BR-3 cells, arrests the cell cycle in the G0/G1 phase, and induces cell apoptosis (apoptosis). Demonstrating strong antiproliferative properties in tumor cell models with minimal damage to healthy cells, EGFR/HER2-IN-16 shows promise for research in breast cancer treatments.
Target-Kategorie:
EGFR|||Apoptosis
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