COX-1/2-IN-9 (Compound 3n) serves as a selective and potent inhibitor of both COX-1 and COX-2, demonstrating IC 50 values of 0.031 µM for COX-1 and 0.01 µM for COX-2. This compound exhibits antibacterial and anti-inflammatory properties, effectively targeting MRSA 1478 (MIC=50 µg/mL) and multidrug-resistant S. lentus (MIC=50 µg/mL). Furthermore, COX-1/2-IN-9 shows promise in relieving MRSA-induced pneumonia in conditions of compromised immunity.
Molekulargewicht:
905.57
Formel:
C30H20IN9O13S2
Target-Kategorie:
Antibacterial|||COX
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
