JAK3-IN-11, CAS [[2412734-00-8]]

Produktübersicht

• Artikelname: JAK3-IN-11, CAS [[2412734-00-8]]
• Artikelnummer: TGM-T9811
• Hersteller Artikelnummer: T9811
• Alternativnummer: TGM-T9811-25MG,TGM-T9811-50MG,TGM-T9811-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

JAK3-IN-11 (Compound 12) exhibits potent, noncytotoxic, irreversible, orally active JAK3 inhibitory activity (IC50 = 1.7 nM) with an excellent selectivity profile (>588-fold compared to other JAK isoforms), covalently binds to the ATP-binding pocket in JAK3. JAK3-IN-11 strongly inhibits JAK3-dependent signaling and T-cell proliferation which is a promising tool for studying autoimmune diseases [1].

Produkteigenschaften

• Molekulargewicht: 401.46
• CAS Nummer: [2412734-00-8]
• Formel: C23H23N5O2
• Target-Kategorie: JAK|||Others

Bilder

T9811