Relatlimab(BMS-986016) is a monoclonal antibody targeting human anti-LAG-3, generated by immunization of transgenic mice with human immunoglobulin carrying recombinant LAG-3 protein.Relatlimab has a blocking effect, blocking the interaction of LAG-3/MHC II (IC50: 0.67 nM) and LAG-3/FGL1 (IC50: 0.019 nM). Relatlimab is often used with Nivoluma to treat advanced melanoma.
Molekulargewicht:
145.2 kDa
Reinheit:
97.20%
CAS Nummer:
[1673516-98-7]
Target-Kategorie:
LAG-3
T9901A-001
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