Inebilizumab(FUT8-KO) is a modified version of inebilizumab that features a knocked-out fucosyltransferase 8 gene (FUT8). This anti-CD19 monoclonal antibody (mAb) exhibits enhanced antibody-dependent cell-mediated cytotoxicity against B cells, making it suitable for research into multiple sclerosis and neuromyelitis optica.
Target-Kategorie:
Immunology/Inflammation related
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