MIL62 is a glycoengineered type II anti-CD20 monoclonal antibody with an Fc region N-glycan that is almost entirely afucosylated. It exhibits increased affinity for the FcgammaRIIIa receptor and possesses direct B-cell killing effects. MIL62 displays antibody-dependent cell-mediated cytotoxicity (ADCC) and is applicable for research in non-Hodgkins lymphoma (NHL).
Target-Kategorie:
Immunology/Inflammation related
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