MAB802 (MRG002 antibody) is a recombinant humanized anti-HER2 monoclonal antibody. It shares the same amino acid sequence as Trastuzumab but is highly fucosylated. The antibody-dependent cell-mediated cytotoxicity (ADCC) activity of MAB802 is comparatively lower. MAB802 is employed as the antibody component in the antibody-drug conjugate Trastuzumab vedotin (MRG002).
Target-Kategorie:
EGFR|||ADC Antibody
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