Olintatug, CAS [[2851870-28-3]] Preis auf Anfrage

Produktübersicht

• Artikelname: Olintatug, CAS [[2851870-28-3]] Preis auf Anfrage
• Artikelnummer: TGM-T9901A-365
• Hersteller Artikelnummer: T9901A-365
• Alternativnummer: TGM-T9901A-365-1MG,TGM-T9901A-365-5MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: 3A4 , ADCT-901 Antibody , Anti-KAAG1 Antibody (ADCT-901)

Produktbeschreibung

Olintatug (ADCT-901) is a highly specialized antibody-drug conjugate (ADC) targeting Kidney-Associated Antigen 1 (KAAG1). It comprises a humanized monoclonal antibody conjugated to a potent pyrrolobenzodiazepine (PBD) dimer cytotoxin via a cathepsin-cleavable linker. Olintatug specifically binds to KAAG1 on tumor cell surfaces, internalizes, and releases the PBD dimer, which induces lethal DNA interstrand cross-links, blocking cell division. It is investigated for KAAG1-expressing solid tumors, including ovarian and triple-negative breast cancers.

Produkteigenschaften

• CAS Nummer: [2851870-28-3]
• Target-Kategorie: Immunology/Inflammation related