Amlenetug (Lu AF82422) is a human monoclonal antibody targeting alpha-synuclein that is in development for multiple system atrophy, demonstrating robust inhibition of alpha-synuclein seeding induced by diverse fibrillar assemblies in mouse primary neurons and by aggregates derived from MSA brain homogenates, while in vivo studies show that both intracerebral co-injection and peripheral administration effectively suppress alpha-synuclein seeding and pathological propagation.
Reinheit:
95.00%
CAS Nummer:
[2850367-41-6]
Target-Kategorie:
Others
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