Carboxymethyl chitosan Methacryloyl (CMCSMA) is a methacryloylated form of carboxymethyl chitosan with properties suitable for 3D printing inks. Composite hydrogels made from this compound can effectively accelerate bone healing in infectious environments, as demonstrated in a rat model with femoral defects infected by Staphylococcus aureus. Carboxymethyl chitosan Methacryloyl requires the presence of a photoinitiator LAP to self-assemble into fibrous hydrogels, targeting bioactive adhesion sites and providing inherent support for tissue cells along with biodegradability. Its applications include cell culture, bio 3D printing, and tissue engineering.
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