DSPE-PEG1000-iRGD is a PEG compound made from DSPE and the alphav-integrin-targeting peptide (iRGD). The iRGD peptide initially binds to alphav-integrins and undergoes proteolytic cleavage within tumors to produce CRGDK/R, which interacts with neuropilin-1, thereby facilitating tumor targeting and penetration. DSPE-PEG1000-iRGD is useful for drug delivery applications.
Target-Kategorie:
Integrin|||Liposome
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