Ganoderiol F has anti-inflammatory, cytotoxic and anti-HIV activity, it inhibits activity of topoisomerases in vitro, and it inhibits human immunodeficiency virus-1 protease with IC(50) values of 20-40 microM. It induced HO-1 expression, activation of the mitogen-activated protein kinase EKR and up-regulation of cyclin-dependent kinase inhibitor p16 and suppressed lipopolysaccharide (LPS)-induced nitric oxide (NO) production.
Molekulargewicht:
454.68
CAS Nummer:
[114567-47-4]
Formel:
C30H46O3
Target-Kategorie:
Autophagy|||Androgen Receptor|||HIV Protease
TMA1012
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