Entrectinib-d8, CAS [[2251773-94-9]] Preis auf Anfrage

Produktübersicht

• Artikelname: Entrectinib-d8, CAS [[2251773-94-9]] Preis auf Anfrage
• Artikelnummer: TGM-TMID-0768
• Hersteller Artikelnummer: TMID-0768
• Alternativnummer: TGM-TMID-0768-10MG,TGM-TMID-0768-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

Entrectinib-d8 (NMS-E628-d8, RXDX-101-d8) is the deuterated form of Entrectinib. Entrectinib (NMS-E628) is an orally bioavailable inhibitor that effectively crosses the blood-brain barrier and exhibits central nervous system activity. It targets TrkA/B/C, ROS1, and ALK with IC50 values of 1, 3, 5, 12, and 7 nM, respectively. Entrectinib induces apoptosis and cell cycle arrest in cancer cells, demonstrates antitumor properties, and alleviates bleomycin-induced pulmonary fibrosis in mice.

Produkteigenschaften

• Molekulargewicht: 568.69
• CAS Nummer: [2251773-94-9]
• Formel: C31H34F2N6O2
• Target-Kategorie: ROS Kinase|||Autophagy|||ALK|||Trk receptor

Bilder

TMID-0768