PTX S1 Protein, Bordetella pertussis, Recombinant (His)

Artikelnummer: TGM-TMPH-00207
Artikelname: PTX S1 Protein, Bordetella pertussis, Recombinant (His)
Artikelnummer: TGM-TMPH-00207
Hersteller Artikelnummer: TMPH-00207
Alternativnummer: TGM-TMPH-00207-5UG,TGM-TMPH-00207-10UG,TGM-TMPH-00207-20UG,TGM-TMPH-00207-50UG,TGM-TMPH-00207-100UG,TGM-TMPH-00207-200UG,TGM-TMPH-00207-500UG
Hersteller: TargetMol
Kategorie: Biochemikalien
Alternative Synonym: Pertussis toxin subunit 1 , PTX S1 , Islet-activating protein S1 (IAP S1) , ptxA , NAD-dependent ADP-ribosyltransferase
S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G proteins. In the absence of G proteins it also catalyzes the cleavage of NAD(+) into ADP-ribose and nicotinamide. It irreversibly uncouples the G-alpha GTP-binding proteins from their membrane receptors. PTX S1 Protein, Bordetella pertussis, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 28.2 kDa and the accession number is P04977.
Molekulargewicht: 28.2 kDa (predicted)
TMPH-00207