ZNRF3 Protein, Human, Recombinant (His)

Produktübersicht

• Artikelname: ZNRF3 Protein, Human, Recombinant (His)
• Artikelnummer: TGM-TMPH-01275
• Hersteller Artikelnummer: TMPH-01275
• Alternativnummer: TGM-TMPH-01275-1MG,TGM-TMPH-01275-5UG,TGM-TMPH-01275-10UG,TGM-TMPH-01275-20UG,TGM-TMPH-01275-50UG,TGM-TMPH-01275-100UG,TGM-TMPH-01275-200UG,TGM-TMPH-01275-500UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: E3 ubiquitin-protein ligase ZNRF3 , KIAA1133 , RING-type E3 ubiquitin transferase ZNRF3 , ZNRF3 , RNF203 , RING finger protein 203 , Zinc/RING finger protein 3

Produktbeschreibung

E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone. Along with RSPO2 and RNF43, constitutes a master switch that governs limb specification.

Bilder

TMPH-01275