MORC3 Protein, Human, Recombinant (His & SUMO)

Produktübersicht

• Artikelname: MORC3 Protein, Human, Recombinant (His & SUMO)
• Artikelnummer: TGM-TMPH-01697
• Hersteller Artikelnummer: TMPH-01697
• Alternativnummer: TGM-TMPH-01697-1MG,TGM-TMPH-01697-5UG,TGM-TMPH-01697-10UG,TGM-TMPH-01697-20UG,TGM-TMPH-01697-50UG,TGM-TMPH-01697-100UG,TGM-TMPH-01697-200UG,TGM-TMPH-01697-500UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: NXP2 , Nuclear matrix protein 2 , Zinc finger CW-type coiled-coil domain protein 3 , KIAA0136 , MORC family CW-type zinc finger protein 3 , MORC3 , ZCWCC3

Produktbeschreibung

Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism. Sumoylated MORC3-NBs can also associate with PML-NBs. Recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity. Binds RNA in vitro. May be required for influenza A transcription during viral infection. Histone methylation reader which binds to non-methylated (H3K4me0), monomethylated (H3K4me1), dimethylated (H3K4me2) and trimethylated (H3K4me3) Lys-4 on histone H3. The order of binding preference is H3K4me3 > H3K4me2 > H3K4me1 > H3K4me0.

Bilder

TMPH-01697