TRAF3 Protein, Human, Recombinant

Produktübersicht

• Artikelname: TRAF3 Protein, Human, Recombinant
• Artikelnummer: TGM-TMPH-02208
• Hersteller Artikelnummer: TMPH-02208
• Alternativnummer: TGM-TMPH-02208-1MG,TGM-TMPH-02208-5UG,TGM-TMPH-02208-10UG,TGM-TMPH-02208-20UG,TGM-TMPH-02208-50UG,TGM-TMPH-02208-100UG,TGM-TMPH-02208-200UG,TGM-TMPH-02208-500UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: LMP1-associated protein 1 (LAP1) , CD40 receptor-associated factor 1 (CRAF1) , TNF receptor-associated factor 3 , CAP-1 , TRAFAMN , TRAF3 , RING-type E3 ubiquitin transferase TRAF3 , CRAF1 , CD40-binding protein (CD40BP)

Produktbeschreibung

Regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of B-cell survival. Part of signaling pathways leading to the production of cytokines and interferon. Required for normal antibody isotype switching from IgM to IgG. Plays a role T-cell dependent immune responses. Plays a role in the regulation of antiviral responses. Is an essential constituent of several E3 ubiquitin-protein ligase complexes. May have E3 ubiquitin-protein ligase activity and promote Lys-63-linked ubiquitination of target proteins. Inhibits activation of NF-kappa-B in response to LTBR stimulation. Inhibits TRAF2-mediated activation of NF-kappa-B. Down-regulates proteolytic processing of NFKB2, and thereby inhibits non-canonical activation of NF-kappa-B. Promotes ubiquitination and proteasomal degradation of MAP3K14.

Bilder

TMPH-02208