Zinc finger Ran-binding domain-containing protein 1 , TRABID , Ubiquitin thioesterase ZRANB1 , ZRANB1 , TRAF-binding domain-containing protein (hTrabid)
Specifically hydrolyzes Lys-29-linked and Lys-33-linked diubiquitin. Also cleaves Lys-63-linked chains, but with 40-fold less efficiency compared to Lys-29-linked ones. Positive regulator of the Wnt signaling pathway that deubiquitinates APC protein, a negative regulator of Wnt-mediated transcription. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. May also modulate TNF-alpha signaling. ZRANB1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 88.4 kDa and the accession number is Q9UGI0.
Molekulargewicht:
88.4 kDa (predicted)
TMPH-02287
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