BNIP3 Protein, Mouse, Recombinant (Cell-Free, His)

Produktübersicht

• Artikelname: BNIP3 Protein, Mouse, Recombinant (Cell-Free, His)
• Artikelnummer: TGM-TMPH-02536
• Hersteller Artikelnummer: TMPH-02536
• Alternativnummer: TGM-TMPH-02536-5UG,TGM-TMPH-02536-10UG,TGM-TMPH-02536-20UG,TGM-TMPH-02536-50UG,TGM-TMPH-02536-100UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 , Bnip3 , Nip3

Produktbeschreibung

Apoptosis-inducing protein that can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane may play a critical role in the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. Plays an important role in the calprotectin (S100A8/A9)-induced cell death pathway.

Produkteigenschaften

• Molekulargewicht: 23.8 kDa (predicted)

Bilder

TMPH-02536