Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments. Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling. Is very specific to hyaluronan, not able to cleave chondroitin sulfate or dermatan sulfate.
Molekulargewicht:
21.7 kDa (predicted)
TMPH-02572
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