Fukutin Protein, Mouse, Recombinant (His & Myc)

Produktübersicht

• Artikelname: Fukutin Protein, Mouse, Recombinant (His & Myc)
• Artikelnummer: TGM-TMPH-02666
• Hersteller Artikelnummer: TMPH-02666
• Alternativnummer: TGM-TMPH-02666-1MG,TGM-TMPH-02666-5UG,TGM-TMPH-02666-10UG,TGM-TMPH-02666-20UG,TGM-TMPH-02666-50UG,TGM-TMPH-02666-100UG,TGM-TMPH-02666-200UG,TGM-TMPH-02666-500UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: Fukuyama-type congenital muscular dystrophy protein , Ribitol-5-phosphate transferase FKTN , Fktn , Fcmd , Fukutin , Ribitol-5-phosphate transferase

Produktbeschreibung

Catalyzes the transfer of CDP-ribitol to the distal N-acetylgalactosamine of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1). This constitutes the first step in the formation of the ribitol 5-phosphate tandem repeat which links the phosphorylated O-mannosyl trisaccharide to the ligand binding moiety composed of repeats of 3-xylosyl-alpha-1,3-glucuronic acid-beta-1. Required for normal location of POMGNT1 in Golgi membranes, and for normal POMGNT1 activity. May interact with and reinforce a large complex encompassing the outside and inside of muscle membranes. Could be involved in brain development (Probable).

Bilder

TMPH-02666