GRO beta/CXCL2 Protein, Mouse, Recombinant

Produktübersicht

• Artikelname: GRO beta/CXCL2 Protein, Mouse, Recombinant
• Artikelnummer: TGM-TMPJ-00011
• Hersteller Artikelnummer: TMPJ-00011
• Alternativnummer: TGM-TMPJ-00011-1MG, TGM-TMPJ-00011-5UG, TGM-TMPJ-00011-10UG, TGM-TMPJ-00011-20UG, TGM-TMPJ-00011-50UG, TGM-TMPJ-00011-100UG, TGM-TMPJ-00011-200UG, TGM-TMPJ-00011-500UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: Gro-beta , GRO beta , GROB , melanoma growth stimulatory activity beta , GRO2 , melanoma growth stimulatory activity beta , MGSA-beta , SCYB2 , MIP2-alpha , Gro-beta , chemokine ligand 2 , MIP2-alpha , MGSA-b , cxcl2 , Macrophage Inflammatory Protein-2-alpha , Growth-regulated protein beta , Growth-regulated protein beta , GRO beta , MGSA-beta , Macrophage Inflammatory Protein-2-alpha , MIP2A , MIP-2 , C-X-C motif chemokine 2

Produktbeschreibung

C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. The expression of mouse MIP-2 is stimulated by endotoxin. The mouse MIP-2 shares approximately 63% aa sequence identity with murine KC, another mouse alpha chemokine, which is induced by PDGF. It has been suggested that mouse KC and MIP-2 are the homologs of the human GROs and rat CINCs. Chemotactic for human polymorphonuclear leukocytes but does not induce chemokinesis or an oxidative burst. The expression of MIP-2 was found to be associated with neutrophil influx in pulmonary inflammation and glomerulonephritis, suggesting that MIP-2 may contribute to the pathogenesis of inflammatory diseases.

Bilder

TMPJ-00011