CD82 Protein, Human, Recombinant (hFc)

Artikelnummer: TGM-TMPJ-00157
Artikelname: CD82 Protein, Human, Recombinant (hFc)
Artikelnummer: TGM-TMPJ-00157
Hersteller Artikelnummer: TMPJ-00157
Alternativnummer: TGM-TMPJ-00157-1MG,TGM-TMPJ-00157-5UG,TGM-TMPJ-00157-10UG,TGM-TMPJ-00157-20UG,TGM-TMPJ-00157-50UG,TGM-TMPJ-00157-100UG,TGM-TMPJ-00157-200UG,TGM-TMPJ-00157-500UG
Hersteller: TargetMol
Kategorie: Biochemikalien
Alternative Synonym: Tetraspanin-27 , KAI1 , ST6 , TSPAN27 , TSPAN274F9 , CD82 molecule , Tspan-27 , IA4 , IA4C33 antigen , ST6tspan-27 , Suppressor of tumorigenicity 6 protein , CD82 antigenC33 , KAI1GR15 , Inducible membrane protein R2 , CD82
CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1 suppresses EMT in prostate cancer cells adhered to fibronectin leading to reduced cell migration and invasiveness. CD82/Kai-1 function is important for muscle stem cell function in muscular disorders. Overexpression of CD82/Kai-1 suppresses growth, migration and invasion of oral cancer cells and may be considered as a potential therapeutic target in oral cancer.
Molekulargewicht: 40-60 KDa (reducing condition)
TMPJ-00157