B7-H4 Protein, Rhesus macaque, Recombinant (hFc)

Produktübersicht

• Artikelname: B7-H4 Protein, Rhesus macaque, Recombinant (hFc)
• Artikelnummer: TGM-TMPJ-00175
• Hersteller Artikelnummer: TMPJ-00175
• Alternativnummer: TGM-TMPJ-00175-1MG,TGM-TMPJ-00175-5UG,TGM-TMPJ-00175-10UG,TGM-TMPJ-00175-20UG,TGM-TMPJ-00175-50UG,TGM-TMPJ-00175-100UG,TGM-TMPJ-00175-200UG,TGM-TMPJ-00175-500UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: V-set domain containing T cell activation inhibitor 1 , B7x , B7H4T-cell costimulatory molecule B7x , B7h.5 , V-set domai , FLJ22418 , B7XPRO1291 , T cell costimulatory molecule B7x , B7-H4 , Vtcn1 , B7S1VCTN1 , Immune costimulatory protein B7-H4 , B7S1 , Protein B7S1

Produktbeschreibung

B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. It also involved in promoting epithelial cell transformation.

Produkteigenschaften

• Molekulargewicht: 70-100 KDa (reducing condition)

Bilder

TMPJ-00175