CD172b , CD172 antigen-like family member B , Signal-regulatory protein beta-1 , Signal-regulatory protein beta-1 , SIRP-beta-1 , SIRPB1 , SIRP-beta-1
Signal-regulatory protein beta-1 (SIRPB1, CD172b) is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK.
Molekulargewicht:
45-55 KDa (reducing condition)
TMPJ-00252
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