AMIGO2 Protein, Human, Recombinant (hFc)

Produktübersicht

• Artikelname: AMIGO2 Protein, Human, Recombinant (hFc)
• Artikelnummer: TGM-TMPJ-00320
• Hersteller Artikelnummer: TMPJ-00320
• Alternativnummer: TGM-TMPJ-00320-1MG,TGM-TMPJ-00320-5UG,TGM-TMPJ-00320-10UG,TGM-TMPJ-00320-20UG,TGM-TMPJ-00320-50UG,TGM-TMPJ-00320-100UG,TGM-TMPJ-00320-200UG,TGM-TMPJ-00320-500UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: DEGA , AMIGO-2 , AMIGO2 , ALI1 , Alivin-1 , Amphoterin-Induced Protein 2 , Differentially Expressed in Gastric Adenocarcinomas

Produktbeschreibung

Amphoterin-Induced Protein 2 (AMIGO2) is a single-pass type I membrane protein which belongs to the AMIGO family of immunoglobulin superfamily. Mature AMIGO2 contains an Ig-like C2-type (immunoglobulin-like) domain, 6 LRR (leucine-rich) repeats, a LRRCT domain, as well as a LRRNT domain. AMIGO2 is mainly expressed in in breast, ovary, cervix, and uterus, although lower in lung, colon, and rectum. AMIGO2 required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO2 may mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. AMIGO2 may contribute to signal transduction through its intracellular domain, and may be required for tumorigenesis of a subset of gastric adenocarcinomas.

Bilder

TMPJ-00320