ICAM-1/CD54 Protein, Rhesus macaque, Recombinant (hFc)

Produktübersicht

• Artikelname: ICAM-1/CD54 Protein, Rhesus macaque, Recombinant (hFc)
• Artikelnummer: TGM-TMPJ-00324
• Hersteller Artikelnummer: TMPJ-00324
• Alternativnummer: TGM-TMPJ-00324-1MG,TGM-TMPJ-00324-5UG,TGM-TMPJ-00324-10UG,TGM-TMPJ-00324-20UG,TGM-TMPJ-00324-50UG,TGM-TMPJ-00324-100UG,TGM-TMPJ-00324-200UG,TGM-TMPJ-00324-500UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: Intercellular adhesion molecule 1 , ICAM1 , CD54 , ICAM-1

Produktbeschreibung

Intercellular adhesion molecule 1 (ICAM1) is known as CD54. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. The endothelial expression of ICAM-1 is increased in atherosclerotic and transplant-associated atherosclerotic tissue and animal models of atherosclerosis. Additionally, ICAM-1 has been implicated in the progression of autoimmune diseases. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.

Bilder

TMPJ-00324