IGF2BP-2 Protein, Human, Recombinant (His)

Produktübersicht

• Artikelname: IGF2BP-2 Protein, Human, Recombinant (His)
• Artikelnummer: TGM-TMPJ-00345
• Hersteller Artikelnummer: TMPJ-00345
• Alternativnummer: TGM-TMPJ-00345-1MG,TGM-TMPJ-00345-5UG,TGM-TMPJ-00345-10UG,TGM-TMPJ-00345-20UG,TGM-TMPJ-00345-50UG,TGM-TMPJ-00345-100UG,TGM-TMPJ-00345-200UG,TGM-TMPJ-00345-500UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: IGF-II mRNA-Binding Protein 2 , IGF2 mRNA-Binding Protein 2 , Hepatocellular Carcinoma Autoantigen p62 , IGF2BP2 , VICKZ2 , IMP-2 , VICKZ Family Member 2 , IMP2 , Insulin-Like Growth Factor 2 mRNA-Binding Protein 2

Produktbeschreibung

Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to the 5-UTR of the Insulin-Like Growth Factor 2 (IGF2) mRNA. This binding is isoform-specific. IGF2BP2 may regulate translation of target mRNAs. Genetic variation at the IGF2BP2 gene has been associated with type 2 diabetes (T2D) by genome-wide association studies and by replication analyses.

Bilder

TMPJ-00345